pentobarbital will lessen the extent or influence of atazanavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers can lower panobinostat stages by ~70% and lead to